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oleanolic acid powder

Oleanolic Acid

508-02-1
Product Name: Oleanoic acid
Appearance: White powder
CAS number 508-02-1
Molecular weight 456.700
Molecular formula C30H48O3
 
Product Name
Oleanic acid
Appearance
White crystalline powder 
Specification
99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months 
 
Oleanolic acid is a pentacyclic triterpenoid isolated and extracted from the fruits of the whole herb or chasteberry of the genus Swertia, family Gentianaceae, and is present in a wide range of plants as both free and liganded forms. Oleanolic acid is widely present in plants, with a general content of 0.2% to 2%. Cucurbitaceae plant rosmarinus officinalis has a higher content of 1.5% to 2% and chasteberry fruit contains 0.6% to 0.7%. Oleanolic acid is white needle-like crystals (ethanol), odourless and tasteless. It is unstable to acid and alkali. Melting point 308 ~ 310 ° C, [α] 20D + 73.3 ° (c = 0.15, chloroform), insoluble in water, soluble in methanol, ethanol, ether, acetone and chloroform.
Xi'an Huawave Biotech Co., Ltd. is a professional oleanolic acid manufacturer and oleanolic acid supplier. We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.
     

  1. Anticancer Activity:

    • Oleanolic Acid has been shown to suppress the proliferation of cancer cells, including lung carcinoma cells, through various mechanisms.
    • Studies have demonstrated its ability to inhibit the proliferation and invasiveness of Kras-transformed cells via autophagy.
    • It also mediates mitochondrial apoptosis in cancer cells through p38 MAPK signaling.

  2. Anti-inflammatory and Immune-Modulating Effects:

    • Oleanolic Acid modulates the immune-inflammatory response, protecting against cardiac injury in mice with experimental autoimmune myocarditis.
    • It has therapeutic implications for human diseases related to inflammation and autoimmune disorders.

  3. Hepatoprotective and Enzyme-Lowering Effects:

    • Clinically, Oleanolic Acid is used as a hepatoprotective agent to lower enzyme levels in the liver.

  4. Antibacterial Properties:

    • As a broad-spectrum antibacterial agent, Oleanolic Acid has potential applications in treating various infections.
  1. Pharmaceutical Industry:
    • Hepatoprotectant: Oleanolic Acid is used as a hepatoprotectant due to its ability to protect liver cells from damage caused by toxins, alcohol, or drugs.
    • Anti-inflammatory Agent: Its anti-inflammatory properties make it useful in treating conditions such as arthritis and other inflammatory diseases.
    • Antioxidant: As an antioxidant, it helps scavenge free radicals, thus protecting cells from oxidative stress and potential damage.
    • Anticancer Agent: Research suggests that Oleanolic Acid may have anticancer properties, inhibiting the growth and spread of certain cancer cells.
  2. Cosmetics and Skincare:
    • Skin Protection: Its antioxidant and anti-inflammatory properties make it a valuable ingredient in skincare products, helping to protect the skin from environmental damage and reduce inflammation.
    • Anti-aging Effects: By reducing oxidative stress, Oleanolic Acid may contribute to anti-aging effects, helping to maintain skin elasticity and reduce the appearance of wrinkles.
  3. Food Industry:
    • Natural Preservative: Due to its antibacterial properties, Oleanolic Acid can be used as a natural preservative in food products to extend their shelf life.
    • Flavor Enhancer: It may also be used to enhance the flavor of certain foods.
 
 
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