Mulberry Leaf Extract/1-Deoxynojirimycin/1-DNJ
19130-96-2
Product Name: Mulberry Leaf Extract/1-Deoxynojirimycin/1-DNJ
Appearance: Brown powder
Specification: 10:1，20:1, 1-Deoxynojirimycin：1%-10%
Test method: HPLC
CAS No: 19130-96-2
Active ingredients: 1-Deoxynojirimycin
Certificates: ISO,FDA,HACCP,HALAL,KOSHER,etc
Appearance: Brown powder
Specification: 10:1，20:1, 1-Deoxynojirimycin：1%-10%
Test method: HPLC
CAS No: 19130-96-2
Active ingredients: 1-Deoxynojirimycin
Certificates: ISO,FDA,HACCP,HALAL,KOSHER,etc
Product Name | Mulberry Leaf Extract/1-Deoxynojirimycin/1-DNJ | |||
Appearance | Brown powder | |||
Specification | 1%-10% | |||
Test Method | HPLC/UV | |||
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. | |||
Shelf Time | 24 months | |||
What is Mulberry Leaf Extract?
Mulberry leaf comes from the mulberry tree, which is found in China. There are 10 different species of mulberry tree, morus nigra, or black mulberry is the most common. The leaves of a mulberry tree are green and spade shaped.
Mulberry leaf has sweet, bitter and cold properties. It is associated with the Liver and Lung meridians, and functions to clear lung heat and clear fire in the liver. It is also used to stop bleeding, especially in patients who are vomiting blood. Mulberry leaf can inhibit the progress of several bacteria, including S. aureus and hemolytic streptococcus. Mulberry leaf extract 1-deoxynojirimycin powder also has the important function in the management and treatment of diabetes.
Natural Sources: 1-Deoxynojirimycin（DNJ） is extracted from mulberry leaves and root bark, and it also exists in other plants and microorganisms. High levels of DNJ have been found in mulberry trees, with significant variations due to factors such as mulberry variety, medicinal part, seasonal climate, geographical soil, leaf position, and developmental stage.
Microbial Sources: 1-Deoxynojirimycin（DNJ） has been isolated from various streptomycetes and bacilli, as well as from two endophytic bacteria, Staphylococcus maltophilia and Micrococcus luteus, isolated from mulberry trees.
Xi'an Huawave Biotech Co., Ltd. is a professional mulberry leaf extract 1-deoxynojirimycin manufacturer and 1-Deoxynojirimycin supplier . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.
1,α-Glucosidase Inhibitor:1-Deoxynojirimycin(DNJ) is a potent α-glucosidase inhibitor, which can inhibit the activity of sucrose, maltase, α-glucosidase, and α-amylase in the human body, thereby blocking the absorption of sugar and inhibiting the rise in blood glucose levels. This makes it effective in the prevention and treatment of diabetes without altering dietary habits.
2,Antiviral Activity:1-Deoxynojirimycin (DNJ) can inhibit the glycosylation process of glycoproteins on the HIV envelope, and the accumulation of immature glycoproteins may inhibit the replication of MoLV by inhibiting cell fusion, the binding of viruses to host cell receptors, and syncytium formation, thereby inhibiting viral activity.
1,α-Glucosidase Inhibitor:1-Deoxynojirimycin(DNJ) is a highly effective α-glucosidase inhibitor. By inhibiting the enzymes that break down starches and sugars (such as sucrose, maltase, α-glucosidase, and α-amylase), it blocks the absorption of sugar and thus inhibits the rise in blood glucose levels. This makes it an important drug for the treatment of diabetes, especially in controlling postprandial blood glucose levels.
2,Improving Insulin Sensitivity: Studies have shown that 1-Deoxynojirimycin(DNJ) can improve insulin sensitivity in skeletal muscle of db/db mice by activating the insulin signaling PI3K/AKT pathway, thereby alleviating insulin resistance.
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