Asiaticoside
16830-15-2
Product Name: Asiaticoside
Appearance: White powder
CAS number 16830-15-2
Molecular weight 959.12
Molecular formula C48H78O19
Appearance: White powder
CAS number 16830-15-2
Molecular weight 959.12
Molecular formula C48H78O19
Product Name | Asiaticoside | |||
Appearance | White crystalline powder | |||
Specification | 99% | |||
Test Method | HPLC | |||
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. | |||
Shelf Time | 24 months | |||
Asiaticoside is an organic compound with the molecular formula of C48H78O19, white needle-like crystals in pure form, light yellow to light brownish-yellow powder in industrial form; odourless, bitter taste, slightly hygroscopic. Soluble in water, ethanol, insoluble in ether, chloroform. Specific optical rotation [α] 22D-14.4 (ethanol). Mainly extracted from the dried whole herb of Centella aslatica (L.) Urb. in the family Umbelliferae.
Xi'an Huawave Biotech Co., Ltd. is a professional Asiaticoside manufacturer and Asiaticoside supplier . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.
1. Antioxidant Activity
- Scavenging Reactive Oxygen Species (ROS): Asiaticoside exhibits potent antioxidant activity by scavenging ROS, which are harmful molecules that can damage cells and tissues. This helps to protect cells from oxidative stress and reduce the risk of oxidative damage-related diseases.
2. Anti-Inflammatory Effects
- Inhibiting Inflammatory Cytokines: Asiaticoside can inhibit the production and release of inflammatory cytokines, which are signaling molecules that mediate the inflammatory response. This helps to reduce inflammation and alleviate pain and swelling.
- Suppressing Inflammatory Pathways: It also works by suppressing inflammatory pathways, such as the TGF-β/Smad signaling pathway, which is involved in the regulation of cell growth, differentiation, and inflammation.
3. Wound Healing and Skin Repair
- Promoting Fibroblast Proliferation and Migration: Asiaticoside stimulates the proliferation and migration of fibroblasts, which are cells involved in wound healing and tissue repair. This helps to accelerate the wound healing process and reduce scar formation.
- Enhancing Collagen Synthesis: By enhancing collagen synthesis, Asiaticoside helps to strengthen the skin barrier and improve skin elasticity and hydration.
4. Neuroprotective Effects
- Improving Cognitive Function: Studies have shown that Asiaticoside can improve cognitive function and protect the brain from damage caused by neurodegenerative diseases such as Alzheimer's disease.
- Reducing Amyloid Deposition: It has also been found to reduce amyloid deposition in the brain, which is a hallmark of Alzheimer's disease and other neurodegenerative conditions.
5. Cardiovascular Protection
- Blocking Pulmonary Hypertension: Asiaticoside has been shown to block the development of hypoxic pulmonary hypertension in animal models, which is a condition characterized by increased pressure in the pulmonary arteries.
- Improving Cardiovascular Health: By protecting the cardiovascular system, Asiaticoside may help to reduce the risk of heart disease and stroke.
6. Anti-Fibrotic Effects
- Inhibiting Fibroblast Proliferation and Collagen Synthesis: Asiaticoside can inhibit the proliferation of fibroblasts and reduce collagen synthesis, which are key processes involved in fibrosis. This makes it a potential therapeutic agent for the treatment of fibrotic diseases such as liver cirrhosis and kidney fibrosis.
1. Wound Healing and Skin Repair
- Promoting Tissue Regeneration: Asiaticoside stimulates the growth of granulation tissue and accelerates wound healing by promoting the proliferation and migration of fibroblasts and keratinocytes.
- Reducing Scar Formation: By inhibiting the proliferation of fibroblasts and reducing the synthesis of collagen, Asiaticoside can help minimize scar formation and improve the appearance of wounds.
2. Anti-Inflammatory Effects
- Suppressing Inflammatory Responses: Asiaticoside exhibits anti-inflammatory activity by inhibiting the release of inflammatory cytokines and reducing the infiltration of inflammatory cells at the site of injury.
- Alleviating Pain and Swelling: It can also help alleviate pain and swelling associated with inflammatory conditions.
3. Antioxidant Activity
- Protecting Cells from Oxidative Stress: Asiaticoside scavenges reactive oxygen species (ROS) and protects cells from oxidative damage caused by various stressors such as UV radiation or chemical exposure.
- Enhancing Skin Health: By reducing oxidative stress, it can help improve skin elasticity, hydration, and overall skin health.
4. Neuroprotective Effects
- Improving Cognitive Function: Studies have shown that Asiaticoside can improve cognitive function and protect the hippocampus from damage in animal models of Alzheimer's disease.
- Reducing Amyloid Deposition: It may also help reduce the deposition of amyloid plaques in the brain, which is a hallmark of Alzheimer's disease.
5. Cardiovascular Protection
- Blocking Pulmonary Hypertension: Asiaticoside has been shown to block the development of hypoxic pulmonary hypertension, cardiovascular remodeling, and endothelial cell injury in animal models.
- Improving Cardiovascular Health: By protecting the cardiovascular system, it may help reduce the risk of heart disease and stroke.
6. Cosmetic Applications
- Anti-Aging Effects: Due to its antioxidant and anti-inflammatory properties, Asiaticoside is often used in cosmetic products to reduce the signs of aging such as wrinkles and fine lines.
- Improving Skin Barrier Function: It can also help strengthen the skin barrier and improve skin hydration and elasticity.
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