phylloquinone

Vitamin K1/phylloquinone

84-80-0
Appearance:White powder
Product Code:HWSW414
Specification: 98%
Certifications:ISO,HACCP,FDA,SC,HALAL,etc
Product grade:USP/Food Grade
Packing: 1kg/aluminum foil bag ,25kg/drum ,OEM package available.
Delivery:5-7 days
MOQ:1KG
 
Product Name
Vitamin K1/phylloquinone/VK1 powder price
Appearance
White powder 
Specification
99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months 
 
Vitamin K1, also known as phylloquinone, is a fat-soluble vitamin primarily involved in blood clotting and bone health. It is predominantly found in green leafy vegetables and plays a critical role in activating proteins necessary for various physiological processes.
     
  Xi'an Huawave Biotech Co., Ltd. is a professional Vitamin K1 manufacturer and Vitamin K1 supplier . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.

Functions of Vitamin K1:

  1. Blood Clotting (Coagulation)

    • Vitamin K1 is essential for synthesizing clotting factors (II, VII, IX, and X) in the liver.
    • Prevents excessive bleeding by enabling proper coagulation in response to injury.
  2. Bone Health

    • Activatesosteocalcin, a protein that binds calcium to the bone matrix, promoting bone mineralization and strength.
    • Reduces the risk of osteoporosis and fractures, especially in older adults.
  3. Cardiovascular Health

    • Supports the regulation of calcium in blood vessels by activating matrix Gla-protein (MGP), which prevents calcium buildup and vascular calcification.
  4. Cellular Functions

    • Plays a role in cell growth, survival, and apoptosis (programmed cell death), contributing to overall cellular health.
 

Applications of Vitamin K1:

  1. Prevention and Treatment of Bleeding Disorders

    • Administered to treat or prevent conditions related to vitamin K deficiency, such as:
      • Hypoprothrombinemia: Low levels of blood clotting factors.
      • Excessive bleeding caused by anticoagulant medications (e.g., warfarin overdose).
      • Hemorrhagic disease of the newborn (HDN): Prevented by routine administration of vitamin K1 at birth.
  2. Bone Health Support

    • Used in supplements to improve bone density and reduce the risk of osteoporosis and fractures, particularly in postmenopausal women and older adults.
  3. Cardiovascular Health

    • Helps prevent vascular calcification and reduces the risk of arterial stiffness and cardiovascular diseases.
  4. Support for Liver Health

    • Helps in maintaining proper blood clotting in individuals with liver disorders that impair clotting factor production.
  5. Dietary Supplements

    • Included in multivitamins or standalone supplements to ensure adequate intake, particularly in populations with poor diets or fat malabsorption conditions.
  6. Surgical and Medical Use

    • Administered before surgery to ensure proper clotting and reduce bleeding risks in patients at risk of deficiency.
    • Key Applications in Specific Populations:
    • Newborns

      • Routine vitamin K1 injections are given to prevent hemorrhagic disease of the newborn, as babies are born with low levels of vitamin K.
    • Elderly

      • Often supplemented to support bone health and reduce the risk of fractures and cardiovascular calcification.
    • Patients on Long-term Anticoagulant Therapy

      • Vitamin K1 levels must be monitored to maintain a balance between preventing clotting and avoiding excessive bleeding.

Sources of Vitamin K1:

  1. Natural Food Sources

    • Green leafy vegetables (spinach, kale, collard greens, broccoli).
    • Vegetable oils (soybean oil, canola oil).
    • Fruits (kiwi, avocado).
  2. Supplements

    • Available as standalone vitamin K1 or in combination with other nutrients like calcium, vitamin D, or magnesium to support bone health.