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Thymosin α1

Thymosin alpha1

62304-98-7
Density: 1.4± 0.1g /cm3
Boiling point :2899.7±65.0 °C at 760 mmHg
Molecular formula: C129H215N33O55
Molecular weight: 3108.275
Flash point: 1707.5±34.3 °C
Accurate mass: 3106.504150
PSA :1456.35000
LogP: -9.87
Appearance: white powder
Vapor pressure: 0.0±0.6 mmHg at 25°C
Refractive index: 1.563
Storage condition: −20°C
 
Product Name
Thymosin alpha1/thymosin α1/
Appearance
White powder 
Specification
98%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months 
 
Thymosin α1 (Tα1) is a peptide originally derived from the thymus gland. It plays a critical role in modulating immune responses and has gained attention for its therapeutic potential in various diseases.
     
  Xi'an Huawave Biotech Co., Ltd. is a professional Thymosin alpha1 manufacturers and Thymosin alpha1 suppliers . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.

Functions of Thymosin α1:

  1. Immune Modulation:

    • Enhances T-cell differentiation and activity, particularly cytotoxic T cells and helper T cells.
    • Stimulates the production and maturation of dendritic cells.
    • Promotes the activation of natural killer (NK) cells.

  2. Anti-Inflammatory Effects:

    • Balances immune responses by reducing excessive inflammation.
    • Modulates cytokine production, including increasing interferon-γ (IFN-γ) and interleukin-2 (IL-2).

  3. Antiviral Activity:

    • Boosts the body's innate immune system, aiding in the clearance of viral infections.
    • Enhances the antiviral activity of interferons.

  4. Antitumor Properties:

    • Supports immune surveillance by activating immune cells to target tumor cells.
    • May help restore immune function in immunosuppressed cancer patients.

  5. Promotion of Tissue Repair:

    • Facilitates tissue regeneration by enhancing cellular repair mechanisms.

Applications of Thymosin α1:

  1. Treatment of Viral Infections:

    • Hepatitis B and C: Used as an adjunctive therapy to improve immune response and aid in viral clearance.
    • COVID-19: Explored for its immune-boosting properties in mitigating severe symptoms and complications.

  2. Cancer Therapy:

    • As part of immunotherapy regimens, particularly in combination with chemotherapy or other immune-stimulating agents, for cancers such as melanoma, lung cancer, and breast cancer.

  3. Immunodeficiency Disorders:

    • Used in treating conditions associated with weakened immune systems, such as HIV/AIDS or immune system deficiencies due to chemotherapy.

  4. Sepsis and Critical Illness:

    • Helps regulate the immune system in critically ill patients, potentially reducing mortality in sepsis.

  5. Autoimmune Diseases:

    • May help balance overactive immune responses in conditions like lupus or rheumatoid arthritis.

  6. Adjunct to Vaccines:

    • Enhances vaccine efficacy by boosting the immune response, particularly in elderly or immunocompromised individuals.
Thymosin α1 is approved in several countries for specific indications, such as chronic hepatitis B and as an immunomodulator. It is under investigation in various clinical trials for broader applications, including emerging infectious diseases and cancer therapies.
 
 
 
 
 
 
 
 
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