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l histidine supplement

L-Histidine

71-00-1
Product Name : L-Histidine
Appearance : White powder
CAS No. : 71-00-1
Product Code: HWSWLZAS
Specification: 98%
Certifications：ISO,HACCP,FDA,SC,HALAL and so on
Product grade:Food grade,USP grade
Delivery：Shipped on the same day from stocks
MOQ：1KG
 
Product Name
L-Histidine
Appearance
White crystalline powder 
Specification
99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months 
 
L-Histidine an alpha-amino acid with the chemical formula C6H9N3O2, was first isolated in 1896 by the German physicist Ebrich Kossel. In the context of nutrition, histidine is considered an essential amino acid for humans, primarily for children. In adulthood, humans begin to be able to synthesise histidine on their own. When small amounts of histidine are added to the diets of chronic uremic patients, the rate of amino acid incorporation into haemoglobin is increased and nephrogenic anaemia is reduced, so histidine is also an essential amino acid for uremic patients. Under the action of histidine decarboxylase, histidine decarboxylates to form histamine. Histamine has a strong vasodilatory effect and is associated with a variety of allergic reactions and inflammation. [2] In addition, histamine stimulates pepsin and gastric acid.
Xi'an Huawave Biotech Co., Ltd. is a professional L-Histidine manufacturers and L-Histidine powder suppliers . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.
     

The efficacy of L-Histidine can be summarized as follows:

  1. Essential Amino Acid for Protein Synthesis: L-Histidine is one of the 22 protein amino acids and plays a crucial role in protein synthesis. It contributes to the growth and development of cells, tissues, and organs in the human body.
  2. Antioxidant and Anti-inflammatory Properties: L-Histidine possesses antioxidant and anti-inflammatory characteristics, which help protect cells from oxidative stress and inflammation, thereby maintaining the normal physiological functions of the body.
  3. Involved in Histamine Production: L-Histidine is a precursor for histamine, a neurotransmitter involved in immune responses, including allergic reactions and digestive functions. It also plays a role in regulating gastric acid secretion and promoting digestive absorption.
  4. Promotes Sleep and Relieves Anxiety: L-Histidine can affect the balance of neurotransmitters in the central nervous system through the synthesis of 5-hydroxytryptamine, indirectly exerting a sedative and hypnotic effect. It has anti-anxiety and anti-depressive properties.
  5. Auxiliary Treatment for Certain Diseases: L-Histidine has auxiliary therapeutic effects on peptic ulcer, anemia, and arthritis. It can promote the formation of gastric mucosa, help absorb iron in the body, and improve symptoms of arthritis.
  6. pH Buffering and Metal Ion Chelation: L-Histidine plays a unique role in proton buffering, metal ion chelation, and scavenging reactive oxygen and nitrogen species, contributing to the maintenance of internal environment stability in the body.

In summary, L-Histidine is an amino acid with multiple benefits for human health, involving various physiological processes such as protein synthesis, antioxidant and anti-inflammatory effects, histamine production, sleep promotion, anxiety relief, and auxiliary treatment for certain diseases. However, it should be noted that excessive intake may also bring adverse effects, so it is recommended to obtain L-Histidine through a balanced diet and follow medical advice for supplementary use.

The uses of L-Histidine are diverse and span multiple fields, particularly in the pharmaceutical, nutritional supplement, and food industries. Here are some key applications of L-Histidine:

  1. Pharmaceutical Applications:

    • Drug Development and Synthesis: L-Histidine serves as an important structural unit in the synthesis of various biologically active compounds, such as antibiotics, anticancer drugs, and antivirals.
    • Adjuvant or Stabilizer in Drugs: It is used as an adjuvant or stabilizer to enhance the stability and bioavailability of drugs.
    • Pharmaceutical Formulations: L-Histidine is used in the preparation of oral solutions, injections, and soft capsules to improve drug solubility and stability.

  2. Therapeutic Uses:

    • Adjuvant Therapy for Diseases: L-Histidine has antioxidant and anti-inflammatory properties, which can help reduce inflammation and promote tissue repair. It is used as adjuvant therapy for liver diseases, infections, and wounds.
    • Improving Muscle Function and Athletic Performance: L-Histidine can improve muscle function and athletic performance, making it beneficial for athletes and patients with muscle diseases.

  3. Nutritional Supplement:

    • Amino Acid Supplement: As an amino acid supplement, L-Histidine provides necessary nutritional support for the body, maintaining normal metabolism and health.
    • Increasing Protein Intake: It is used to increase protein intake, promote muscle growth and repair, and regulate immune function in certain situations.

  4. Food Industry:

    • Food Additive: L-Histidine can be used as a food additive to enhance the nutritional value and flavor of food products.
    • Chemical Leavening Agent in Bread Manufacturing: It can be used to improve the aroma of bread during manufacturing.

  5. Biochemical Research:

    • Research Reagent: L-Histidine is also used in biochemical research as a research reagent for various experiments and studies.

In summary, L-Histidine has a wide range of applications due to its unique chemical properties and physiological functions. It plays a crucial role in the pharmaceutical, nutritional supplement, food, and biochemical research industries.

 
 
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