Avanafil

Xi'an Huawave Biotech Co., Ltd. is a professional Avanafil manufacturer and Avanafil supplier . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.
Avanafil is a pharmaceutical ingredient mainly used to treat male erectile dysfunction (ED), with various effects and functions, as follows:
1，Improving erectile dysfunction: Avanafil is a novel phosphodiesterase 5 inhibitor (PDE5i), which is currently approved in China for the treatment of penile erectile dysfunction. It inhibits the activity of PDE5 enzyme, prevents the degradation of cGMP (cyclic guanosine monophosphate), thereby increasing the level of cGMP in the penile sponge, causing smooth muscle relaxation, increasing penile blood flow, and improving erectile function.
2，Increasing penile blood flow: Avanafil dilates penile blood vessels, promoting blood flow into the corpus cavernosum of the penis, thereby increasing congestion and making erections harder and more durable.

3，Extended ejaculation latency: Avanafil can delay the central nervous system's control over ejaculation, reduce the brain's premature triggering of ejaculation, and thus prolong the ejaculation latency.
4，Relieve premature ejaculation: Avanafil can reduce the excitability of the central nervous system, decrease sensitivity to ejaculation, and help alleviate premature ejaculation symptoms.
5，Enhancing libido: Avanafil may affect an individual's sexual desire and behavior by regulating the balance of neurotransmitters such as dopamine, thereby increasing libido.

1. Drug characteristics
Fast onset of action: As a new type of phosphodiesterase 5 inhibitor (PDE5i), Avanafil tablets have a higher affinity for PDE5 enzyme and a faster onset time, reaching maximum blood drug concentration in 0.5-0.75 hours.
Long duration: Typically, the medication lasts for 3-5 hours and takes 10-15 minutes to take effect, and is not affected by a normal diet. However, high-fat foods may prolong the duration of the medication's effect.
Less adverse reactions: Due to its higher selectivity towards PDE5 enzyme, the incidence and severity of adverse reactions are relatively low. Common adverse reactions after taking Avanafil tablets include headache, facial flushing, nasal congestion, etc., which are usually mild and tolerable. The incidence of indigestion, visual abnormalities, and lower back pain is significantly lower than other PDE5i.
2. Precautions
Avanafil is a prescription drug and should be taken under the guidance of a doctor. It cannot be taken without authorization.
Patients with erectile dysfunction should maintain a regular sleep schedule, avoid staying up late, and engage in more exercise in addition to taking Avastin.
During the period of taking Avastin tablets, it is necessary to strengthen physical exercise, such as jogging, cycling, climbing stairs, etc., to accelerate the body's metabolism and facilitate the absorption of drug ingredients.
Avanafil tablets should not be taken in excess, as they can damage the cardiovascular and endocrine systems, causing symptoms such as elevated blood pressure, palpitations, and blood sugar. They may also damage the respiratory system and skin, leading to adverse reactions such as coughing, nasal bleeding, rash, and skin itching. After stopping taking medication, it usually subsides on its own without the need for special treatment.