NAD+

NAD+

76961-04-1
Appearance:White powder
Product Code:HWSW598
Specification: 99%
Certifications:ISO,HACCP,FDA,SC,HALAL,etc
Product grade:USP/Food Grade
Packing: 500mg/vial
Delivery:5-7 days
 
Product Name
NAD+
Appearance
White powder 
Specification
99%
Test Method
HPLC
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Time
24 months 
NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in all living cells. It plays a central role in cellular metabolism, energy production, and many biological processes.
     
  Xi'an Huawave Biotech Co., Ltd. is a professional NAD+ manufacturer and NAD+ supplier . We are committed to providing customers with professional research and development, production and sales, as well as OEM and ODM processing services.

🔬Function of NAD+

  1. Energy Metabolism (Redox Reactions)

    • Acts as an electron carrier in redox reactions.

    • Alternates between oxidized form (NAD⁺) and reduced form (NADH).

    • Essential in glycolysis, the Krebs cycle, and oxidative phosphorylation.

  2. DNA Repair

    • Serves as a substrate for enzymes like PARPs (Poly ADP-ribose polymerases) involved in repairing damaged DNA.

  3. Gene Expression

    • Regulates activity of sirtuins, a family of NAD⁺-dependent deacetylases that influence aging, inflammation, and stress responses.

  4. Cell Signaling

    • Used in pathways like calcium signaling via CD38 and CD157 enzymes.

🧪Applications of NAD+

  1. Aging & Longevity Research

    • NAD⁺ levels decline with age.

    • Boosting NAD⁺ via precursors (e.g., NMN,NR) is linked to improved mitochondrial function and extended healthspan in animal studies.

  2. Neurodegenerative Diseases

    • NAD⁺ supports neuronal health.

    • Investigated for roles in Alzheimer’s, Parkinson’s, and ALS.

  3. Metabolic Disorders

    • Shown to improve insulin sensitivityandmitochondrial function, possibly benefiting type 2 diabetes and obesity.

  4. Cardiovascular Health

    • May protect the heart by improving mitochondrial efficiency and reducing oxidative stress.

  5. Immunology and Inflammation

    • Sirtuin activation by NAD⁺ modulates immune response and inflammation.

  6. Cancer Research

    • Targeting NAD⁺ metabolism is a strategy in certain cancers (e.g., inhibiting PARPs or NAD+ biosynthesis enzymes).